Medications To Lower Cholesterol Level

Medications To Lower Cholesterol Level 5.00/5 (100.00%) 5 votes

*The drug prescribed will depend on the individual, the cholesterol level, other problems, and the doctor’s preferences.

Nicotinic acid derivatives

  • Nicotinic acid (niacin) has proven cholesterol-lowering effects when given in daily doses exceeding 1 gram. However, such doses cause flushing and rashes. Treatment with nicotinic acid should be supervised by a doctor, who can advise on how to increase the dosage over three or four weeks and minimise the risk of side effects.
  • Besides nicotinic acid/niacin preparations, there is a nicotinic acid derivative, acipimox (Olbetam). Side effects are less of a problem with this drug, and it may well be the drug of choice if dietary and lifestyle modifications prove ineffective, although safety in long-term use has not been established.

- These drugs can reduce LDL cholesterol levels by as much as 18%, and at the same time raise HDL cholesterol levels.

  • – Bezafibrate (Bezalip). Its primary effect is to reduce triglyceride levels. It also increases the breakdown of LDL particles, thus lowering the LDL Cholesterol level in the bloodstream.
  • – Clofibrate (Atromid-S) is gradually becoming obsolete. New derivatives have proved just as effective with fewer side effects.
  • – Fenofibrate (Lipanthyl) lowers VLDL and LDL cholesterol levels and raises HDL levels.
  • – Gemfibrozil (Lopid) reduces VLDL and LDL cholesterol by decreasing the synthesis of VLDL in the liver. It also raises low levels of HDL cholesterol.
  • – Ciprofibrate (Modalim) reduces VLDL and LDL cholesterol levels.

Symptoms, Types and Treatment Options for Warts

Symptoms, Types and Treatment Options for Warts 5.00/5 (100.00%) 8 votes

Warts SymptomsNowadays, many health issues are being caused because of viral infection. One such health issue caused due to virus is warts. Warts are small growths caused in the skin by viral infection. The virus is known to infect the surface layer of the skin and this virus is regarded as the member of the Human Papilloma Virus (HPV) family.

Warts are communicable from one part of the body to another part of the body and from one person to another as well. So, if any of the family member suffer from this health issue, the others should be careful. The warts can broadly be classified into four major categories; they are common warts, foot warts, flat warts and genital warts.

Some of the warts symptoms are as follows:

Pathophysiology of Circulatory Failure and Cardiopulmonary Resuscitation

Pathophysiology of Circulatory Failure and Cardiopulmonary Resuscitation 5.00/5 (100.00%) 6 votes

Pathophysiology of Circulatory Failure

circulatory failure
Circulatory failure, or the inability of the heart to provide sufficient cardiac output to sat­isfy tissue metabolic requirements, is the most important and most common cause of altered pharmacokinetics during cardiac emergencies. Circulatory failure may result from decreased myocardial contractility, arrhythmias that allow insufficient time for diastolic filling or impair atrioventricular synchrony, circulatory stresses such as increased afterload or hypovolaemia, valvular dysfunction, tamponade, or a variety of less common insults.

Regardless of the aetiology, circulatory fail­ure elicits characteristic compensatory haemodynamic adjustments, mediated in large part by activation of the sympathetic nervous system [Peniel & Benowitz 1984; Benowitz & Meister 1978]. Enhanced sympathetic tone in­creases cardiac contractility and peripheral vas­cular resistance, both of which serve to main­tain arterial blood pressure. The increase in peripheral vascular resistance, however, is not uniform among different vascular beds.

Anaesthetic Agents – Drugs Used in Anaesthesia

Anaesthetic Agents – Drugs Used in Anaesthesia 5.00/5 (100.00%) 4 votes

General Anaesthetic Agents

The mechanism by which anaesthetic drugs produce unconsciousness is still unknown. Meyer in 1899 and Overton in 1901 noted that within any group of drugs, anaesthetic potency correlates well with lipid solubility, and most modern theories agree that the site of action is probably the lipid bilayer of nerve cell mem­branes, or possibly a protein receptor in this sit­uation, but further knowledge is limited.

Inhalational Agents

Anaesthesia Inhalational
Anaesthetic practice is unique in that a high proportion of the drugs are administered by the inhalational route. Such agents must either be gaseous, or the vapour of volatile liquids (Vari­ous Authors 1984).
Of the original three inhalational agents – ni­trous oxide, ether and chloroform – the first two are still used widely.

Synopsis of Important Principles – Drugs in Anaesthetic Practice

Synopsis of Important Principles – Drugs in Anaesthetic Practice 5.00/5 (100.00%) 3 votes

Synopsis of Important Principles
anaesthesia prevention of pain during surgery

  1. The main aim of anaesthesia is the prevention of pain during surgery and at other times.
  2. Anaesthesia involves a balanced approach, in which the individual patient’s psyche and pathophysiology are taken into account and drugs are used to modify and control any aspect as required.
  3. The decision to use a particular drug or technique must be made after careful consideration of the pathophysiological features of the individual case and how these may affect the phar­macokinetic handling and tissue response to the drugs available.
  4. Any associated disease or pathophysiological abnormality should wherever possible be treated or corrected before operation, and potentially dangerous physiological disturbances avoided during and after anaesthesia.
  5. Anaesthetic drugs are relatively non-toxic but there are some important effects. Halothane is occasionally associated with hepatitis and methoxyflurane with kidney damage. Malignant hyperpyrexia, the aetiology of which is uncertain, is a rare but often fatal condition which can be triggered off by several anaesthetic drugs in genetically susceptible individuals.

Cathartics, Enemas and Activated Charcoal

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Cathartics and Enemas

Although the use of cathartics and enemas is traditional, these measures are most unlikely to reduce absorption since this usually occurs rap­idly in the upper small intestine. They can only add to the misery and discomfort of the patient Efficacy in removal of drug has never been es­tablished. In one recent study, saline catharsis had no beneficial effect whatsoever on the ab­sorption of aspirin taken with charcoal (Sketris et al. 1982).

Whole Gut Lavage

One situation where attempts to empty the bowel may be helpful is in poisoning with ‘slow’ or ‘timed release’ formulations. The number of such preparations on the market is increasing and since they usually contain a much larger dose of drug than ordinary tablets, intoxication may be severe and prolonged.

Methods for Enhancement of Drug Elimination

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haemodialysisHaemodialysis, peritoneal dialysis, haemoperfusion, exchange transfusion and forced diuresis have all been used in attempts to increase the rate of removal of drugs and poisons. How­ever, the amount of active drug removed is often disappointingly small, and the indications for the use of such measures is very limited.

Never­theless, poisoned patients are often unnecessar­ily subjected to these potentially harmful meas­ures, and the literature is full of anecdotal accounts of miraculous recovery attributed to such treatment (Winchester et al. 1977). Prop­erly controlled clinical trials are difficult to carry out, and very few have been published. With the possible exception of forced alkaline di­uresis for poisoning with salicylate and long act­ing barbiturates such as phenobarbitone, none of these methods for enhancement of drug re­moval has ever been shown to reduce morbidity or mortality in poisoned patients (Todd 1984).

Indeed, some studies suggest the opposite result. This is not to say that such measures are never necessary, or indeed sometimes life saving, but a more critical appraisal of their role is required.

Treating Diabetes Type2 with Miglitol ( Glyset, Acarbose, Precose )

Treating Diabetes Type2 with Miglitol ( Glyset, Acarbose, Precose ) 4.43/5 (88.57%) 7 votes

Brand name Glyset, Miglitol is prescribed for treating Diabetes Type 2 . This is an Antidiabetic medication. Generic Ingredients are :- Acarbose, Precose.
precose for diabetes

General Information of the drug

  • Miglitol works differently from other oral antidiabetes drugs, which control blood sugar levels by increasing the production of insulin or helping the body to use the hormone more efficiently.
  • Miglitol delays the digestion of carbohydrates (sugars) by acting in the cells that line the small intestine, where sugar is absorbed. This results in less sugar being absorbed into the blood and therefore, a lower blood-sugar level.
  • Miglitol also has some effect against the enzyme lactase, but usually does not cause lactose intolerance. Hypoglycemia (very low blood sugar) is unlikely with miglitol because of the way the drug works in diabetes.

Generalized Anxiety Disorder Treatment with Clorazepate ( Tranxene )

Generalized Anxiety Disorder Treatment with Clorazepate ( Tranxene ) 4.55/5 (90.91%) 11 votes

clorazepate tranxeneA Benzodiazepine sedative class type of dug , Clorazepate is generic drug name for Gen-Xene, Tranxene, Tranxene-SD , Tranxene T-Tab. It is commonly prescribe for treating several conditions :-

General Information of the drug

  • Clorazepate dipotassium is a benzodiazepine, which directly affect the brain. This drug is a central-nervous-system depressant, and can relax you and make you more tranquil or sleepier, or they can slow nervous system transmissions in such a way as to act as an anticonvulsant.

Drug Overdosage and Poisoning – Synopsis of Important Principles

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Synopsis of Important Principles

intensive supportive therapy1. Specific antidotal therapy is available for very few poisons. The mainstay of treatment of severe poisoning is intensive supportive therapy and good nursing care.

2. The great majority of poisoned patients recover with intensive supportive therapy alone, and enthusiastic claims for the success of other treatment often cannot be justified.

3. With some important exceptions, the management of poisoning is not altered by knowledge of plasma drug concentrations. There are many pitfalls in the interpretation of drug concen­trations in poisoned patients, especially when nonspecific analytical methods are used.

Treatments Usage and Effects of Dronabinol Drug (Or Marinol )

Treatments Usage and Effects of Dronabinol Drug (Or Marinol ) 4.50/5 (90.00%) 4 votes

Dronabinol is generic drug name for Marinol , an Antinauseant type of drug. It is prescribed for treating several conditios :-marinol

  • Nausea and vomiting associated with cancer chemotherapy,
  • appetite stimulation and weight-loss prevention in people with acquired immunodeficiency syndrome (AIDS).

General Information

  • Dronabinol is a legal form of marijuana. The psychoactive chemical in marijuana is delta-9-THC. Dronabinol has all of the psychological effects of marijuana and is therefore considered to be a highly abusable drug.
  • Dronabinol increases the effects of alcohol, sleeping pills, sedatives, and other depressants.
  • Dronabinol also enhances the effects of psychoactive drugs including tricyclic antidepressants, amphetamines, cocaine, and other stimulants.

Gastric Aspiration and Lavage

Gastric Aspiration and Lavage 1.00/5 (20.00%) 1 vote

Gastric Aspiration and Lavage

Gastric AspirationAlthough unabsorbed drug in the stomach may be removed by gastric aspiration and lav­age its usefulness in practice has been seriously questioned (Proudfoot 1984). Most drugs and poisons seem to be absorbed rapidly and this technique is unlikely to be productive more than 4 hours after ingestion, unless gastric emptying has been delayed by opioid analgesics, anti­cholinergic agents, central nervous system de­pressants, and possibly salicylates. In such circumstances gastric lavage may be worthwhile up to 12 hours after ingestion.

It is said to be contraindicated after ingestion of corrosives and hydrocarbons such as paraffin because of the risks of perforation and lipoid pneumonia, respectively.

Angiotensin-Converting Enzyme Inhibitor – Vasotec Enalapril

Angiotensin-Converting Enzyme Inhibitor – Vasotec Enalapril 5.00/5 (100.00%) 3 votes

An Angiotensin-Converting Enzyme inhibitor ( or ACE ) , Enalapril is commonly prescribe for treating several conditions :-

  • Hypertension ( high blood pressure ),
  • heart failure,
  • diabetic kidney disease,
  • and heart attack treatment ( when the function of the left ventricle has been affected),
  • kidney failure,
  • kidney hypertension,
  • managing people with a high risk of heart disease,
  • chronic kidney disease,
  • preventing a second stroke.

General Information of the drug

Treating Hypertension with Lexxel Generic Drug

Treating Hypertension with Lexxel Generic Drug 5.00/5 (100.00%) 1 vote

Lexxel is generic drug prescribes for Hypertension. It is of Antihypertensive combination. Generic Drug Ingredients are Enalapril and Felodipine.

General Information

  • Lexxel contains 5 mg of felodipine, a calcium channel blocker, and 5 mg of enalapril, an angiotensin-converting enzyme (ACE) inhibitor. The 2 drugs in this combination belong to widely prescribed groups of hypertension medication.
  • Lexxel is not meant for the initial treatment of hypertension.
  • Most people taking this product have taken 1 of the ingredients as an individual pill and need more medication to control their blood pressure.

Mupirocin as Topical Antibiotic for Skin Infection

Mupirocin as Topical Antibiotic for Skin Infection 3.80/5 (76.00%) 5 votes

Mupirocin is generic drug for Topical Antibiotic usage. Brand Drug prescription – Bactroban. This drug is prescribed for Impetigo (streptococcal skin infections), eczema, inflammation of the hair follicles, and minor bacterial skin infections.

General Information of the drug

  • Mupirocin nasal is used to prevent resistant Staphylococcus aureus infections from spreading during outbreaks of the infection.
  • Mupirocin can also be used to treat diaper rash.
  • Mupirocin is a unique, non-penicillin drug that works against the common microorganisms that cause impetigo in children.
  • It is used to supplement other treatments for impetigo, although many doctors prefer oral medication.
  • Mupirocin works by interfering with bacteria’s ability to make the proteins it needs for survival.
  • Large amounts of mupirocin kill bacteria and smaller amounts stop the bacteria from growing. It may be effective against antibiotic- resistant bacteria.

Achieving Desired Treatment Effect with Cor­rect Drug Dosage via Rational therapeutics

Achieving Desired Treatment Effect with Cor­rect Drug Dosage via Rational therapeutics 5.00/5 (100.00%) 2 votes

Medical LabThe idea that drug concentrations could be measured and used to guide therapeutic deci­sions was first applied to quinidine when it was used to convert the cardiac rhythm of patients with atrial fibrillation to sinus rhythm (Sokolow & Ball 1956).

Although quinidine is rarely used for this purpose today, because of the advent of DC cardioversion, this study is still almost unique because it defined a target concentration based upon both the probability of therapeutic success and of toxicity.

Collaboration Between Healthcare Provider and Clinical Labora­tory on Therapeutic Drug Monitoring

Collaboration Between Healthcare Provider and Clinical Labora­tory on Therapeutic Drug Monitoring 5.00/5 (100.00%) 1 vote

Therapeutic drugTherapeutic drug monitoring is based upon the collaboration between a health care provider (clinician, pharmacist, nurse) responsible for making quantitative and qualitative decisions about drug treatment and the clinical labora­tory providing analytical services for the measurement of drug concentrations. The in­formation provided by a drug concentration measurement is generally greater than for other substances measured by the laboratory.

This is because, unlike say sodium or glucose, the in­take of a drug is quite well known and the pro­cesses of distribution and elimination are usu­ally very simple and not under the control of a multitude of homeostatic controlling reflexes.

Using Entacapone in Parkinson’s Disease Treatment

Using Entacapone in Parkinson’s Disease Treatment 5.00/5 (100.00%) 6 votes

Entacapone ComtanEntacapone is an ‘Antiparkinsonian‘ generic drug for treating Parkinson Disease. Brand Drug prescription – Comtan.

Parkinson’s disease

  • Chronic (persistent) disorder of part of the brain, which affects the way the brain co-ordinates the movements of the muscles in various parts of the body.

General Information of the drug
Entacapone is always used in combination with levodopa + carbidopa. It is prescribed For Parkinson’s disease patients for whom levodopa + carbidopa loses its effectiveness between doses.

Fosfomycin – Urinary anti-infection drug

Fosfomycin – Urinary anti-infection drug 5.00/5 (100.00%) 2 votes

monurolFosfomycin is generic drug for  treating Urinary Anti-Infection. Brand Drug prescription – Monurol.

General Information

  • Prescribed for treating Uncomplicated urinary infection, Fosfomycin kills a variety of bacteria ( by preventing bacteria from sticking to the wall of the urinary tract and by interfering with bacterial cell division).
  • In the body, it is converted to its active form—free fosfomycin.
  • Generally, bacteria that are resistant to other antibiotics are not resistant to fosfomycin, so this drug may work where others have failed.


Do not take fosfomycin if you are allergic or sensitive to any of its ingredients.

Amiodarone – Treating Abnormal Heart Rhythms

Amiodarone – Treating Abnormal Heart Rhythms 5.00/5 (100.00%) 11 votes

AmiodaroneAmiodarone is generic drug name for Cordarone , Pacerone . It is prescribed for treating Abnormal Heart Rhythms.

General Information

  • Amiodarone works by decreasing the sensitivity of heart tissue to nervous impulses within the heart. It should be prescribed only in situations where the abnormal rhythm is so severe as to be life-threatening and does not respond to other drug treatments.
  • It has not been proven that people taking this drug will live longer than those with similar conditions who do not take it.
  • Amiodarone may exert its effects 2-5 days after you start taking it, but often takes 1-3 weeks to affect your heart.
  • Amiodarone’s antiarrhythmic effects can last for weeks or months after you stop taking it.

How does the drug Interact ?

What to Think of When Looking at Portable Massage Tables

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As with all other investments, choosing the right portable massage table can be a challenge. Part of the problem is that there is a wide range of options available from various retailers such as Massage Warehouse and with no experience in the matter, it can be difficult to determine which option is right for the current situation. The good news is that by asking themselves a few simple questions, it becomes much easier for therapists to sort through the various portable massage tables and find the right one for their needs. Here are some of the most important things to consider during this process.

Autism Swings for Your Child

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Autism spectrum disorder is a development disability that begins to show itself in children when they are three years old or younger. Each case of autism is different, though many children really struggle with their motor skills and sensory processing. This is what makes swigs so beneficial to their development and happiness. There are a variety of autism toys, including swings, available that offer different types of movement, sensory and occupational therapy activities.

The Importance of Swings for Children with Autism

One of the major difficulties children with autism face is problems with sensory processing. Just by swinging back and forth or side to side, the child is able to calm their behavior and relax through the repetitive motion. This movement provides amazing sensory input for the child and can also help them focus and motivate them to improve in their social interactions, as well as encouraging better communication skills. Autism swings are often used as part of sensory integration therapy, including helping with visual processing, the vestibular system and proprioception.

Smartly Shopping for Incontinence Products Online

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Incontinence can understandably be a very sensitive issue for people living with it, but it is actually a very common and prevalent medical problem. Adults dealing with this type of challenge need to have products and supplies available that will keep them safe and comfortable. An increasing number of consumers are looking to online sources for their incontinence products. There are many advantages that come with choosing this shopping method.

Finding the Perfect Fit
Most physical stores are not going to have the shelf space to offer a wide range of adult incontinence supplies. They will often have maybe one or two brands, and not much in terms of variety of sizes or styles.

Online retailers often have a lot more freedom and flexibility when it comes to their inventory. They often work directly with the manufacturers of these products, and essentially have entire warehouses of space available to fill with different types of products.