Oral Tag's Archives

Synopsis of Important Principles
anaesthesia prevention of pain during surgery

  1. The main aim of anaesthesia is the prevention of pain during surgery and at other times.
  2. Anaesthesia involves a balanced approach, in which the individual patient’s psyche and pathophysiology are taken into account and drugs are used to modify and control any aspect as required.
  3. The decision to use a particular drug or technique must be made after careful consideration of the pathophysiological features of the individual case and how these may affect the phar­macokinetic handling and tissue response to the drugs available.
  4. Any associated disease or pathophysiological abnormality should wherever possible be treated or corrected before operation, and potentially dangerous physiological disturbances avoided during and after anaesthesia.
  5. Anaesthetic drugs are relatively non-toxic but there are some important effects. Halothane is occasionally associated with hepatitis and methoxyflurane with kidney damage. Malignant hyperpyrexia, the aetiology of which is uncertain, is a rare but often fatal condition which can be triggered off by several anaesthetic drugs in genetically susceptible individuals.

Cathartics and Enemas

Although the use of cathartics and enemas is traditional, these measures are most unlikely to reduce absorption since this usually occurs rap­idly in the upper small intestine. They can only add to the misery and discomfort of the patient Efficacy in removal of drug has never been es­tablished. In one recent study, saline catharsis had no beneficial effect whatsoever on the ab­sorption of aspirin taken with charcoal (Sketris et al. 1982).

Whole Gut Lavage

One situation where attempts to empty the bowel may be helpful is in poisoning with ’slow’ or ‘timed release’ formulations. The number of such preparations on the market is increasing and since they usually contain a much larger dose of drug than ordinary tablets, intoxication may be severe and prolonged.

Lexxel is generic drug prescribes for Hypertension. It is of Antihypertensive combination. Generic Drug Ingredients are Enalapril and Felodipine.

General Information

  • Lexxel contains 5 mg of felodipine, a calcium channel blocker, and 5 mg of enalapril, an angiotensin-converting enzyme (ACE) inhibitor. The 2 drugs in this combination belong to widely prescribed groups of hypertension medication.
  • Lexxel is not meant for the initial treatment of hypertension.
  • Most people taking this product have taken 1 of the ingredients as an individual pill and need more medication to control their blood pressure.

Mupirocin is generic drug for Topical Antibiotic usage. Brand Drug prescription – Bactroban. This drug is prescribed for Impetigo (streptococcal skin infections), eczema, inflammation of the hair follicles, and minor bacterial skin infections.

BACTROBAN
General Information of the drug

  • Mupirocin nasal is used to prevent resistant Staphylococcus aureus infections from spreading during outbreaks of the infection.
  • Mupirocin can also be used to treat diaper rash.
  • Mupirocin is a unique, non-penicillin drug that works against the common microorganisms that cause impetigo in children.
  • It is used to supplement other treatments for impetigo, although many doctors prefer oral medication.
  • Mupirocin works by interfering with bacteria’s ability to make the proteins it needs for survival.
  • Large amounts of mupirocin kill bacteria and smaller amounts stop the bacteria from growing. It may be effective against antibiotic- resistant bacteria.